Pain Management

Pain management is very essential as uncontrolled pain affects the productivity and day to day life of patients. Even if underlying diseases process is stable, unbearable pain prevents the patients from doing their day to day job comfortably and fulfill their roles in the family and society. Chronic pain is much more difficult to manage than acute pain. Chronic pain requires multidisciplinary approach and customized treatment approach. Chronic pain is caused by a number of perpetual factors. Thus, curing chronic pain requires customized treatment to meet the specific needs of individual patients.

Optimal treatment may involve the use of medications that possess pain-relieving properties, including some antidepressants, anticonvulsants, antiarrhythmics, anesthetics, antiviral agents, and NMDA (N-methyl-D-aspartate) antagonists. NMDA-receptor antagonists, such as dextromethorphan and ketamine, can block pain transmission in dorsal horn spinal neurons, reduce nociception, and decrease tolerance to and the need for opioid analgesics. [Anesth Analg 2001 Mar;92(3):739-44] It is observed that smaller concentration of each medication can be more effective in treating sensation of pain.

To provide high local concentration at the site of application, for trigger point application, or in a base that allows systematic absorption, topical and transdermal creams and gels can be formulated. Various studies have shown that there is no restriction on what type of drugs can be incorporated into a properly compounded transdermal gel. Another advantage of using medication topically is, side effects associated with oral medication can be avoided. When medications are administered transdermally, they are not absorbed through the gastrointestinal system and do not undergo first-pass hepatic metabolism.

Pharmacena works closely with patients and practitioners to solve the problems by customizing medications that fulfill the specific needs of individual patients. Our compounding pharmacists are available to discuss the details of dosages, strengths, medications and combinations appropriate for individual patients. Close coordination with practitioner and patient ensures that we provide tailor made medication to meet the specific needs of your patients.